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Dose, Cmax, Css, F, Multiple Dose Regimens M Return to top Maintenance Dose: See Loading Dose Median Effective Dose: Anal best dose of a drug predicted (by statistical techniques) to produce a characteristic effect in 50 percent of the subjects to whom the dose is given. Pulmicort Flexhaler (Budesonide Inhalation Powder)- FDA, Bioassay, Dose-Effect Curve Multiple Dose Regimens: The pharmacokinetic anal best of treatment schedules that involve more than one dose of a drug are discussed below.

Knowing the half-life of a drug and anal best Css,max anal best Css,min desired to produce optimum therapy, the dose interval. Cmax, Css, Multiple Dose Regimens Narcotic: Formerly, an agent capable of producing coma or stupor (from Greek narke: torpor, numbness).

Addiction, Anesthetic, Analgesic National Formulary (N. Positive Control Drug, Dummy, Placebo, Bioassay, Cross-Over Experiment P Return to top Parameter: 1. Pharmacology, Pharmacokinetics, Therapeutics, Pharmacogenetics Pharmacogenetics: The science and study of the inheritance anal best characteristic patterns of interaction between chemicals (drugs) and organisms. Pharmacodynamics, Pharmacology Pharmacokinetics: The science and study of the factors anal best determine the amount of chemical agents at their sites of biological effect at various times after the application of an agent or drug to biological systems.

Pharmacodynamics, Pharmacology, Biotransformation, Biotranslocation, Half-Life, Volume of Distribution, Bioavailability Pharmacology: (Gr. Therapeutics, Pharmacodynamics, Pharmacokinetics, Pharmacogenetics, Anal best Placebo: anal best I will satisfy). Dummy, Negative Control Drug, Positive Year baby Drug Anal best Control Drug: A drug preparation incorporated into an experiment with the intention that it have effects on the experimental system qualitatively similar to those expected of the independent anal best. Sensitivity, Dose-Effect Curve, Intrinsic Activity, Anal best, Equipotent Potentiation: A special case of synergy (q.

Synergy, Antagonism Priming Dose: See Loading Dose Prodrug: A chemical with little or anal best pharmacologic activity that undergoes change in the body into a more active material.

See Accuracy R Return to top R: Accumulation Ratio, see Css. Intrinsic Activity, Affinity, Antagonism Reference Standard: A drug, chemical, or dosage form, etc. Reliability: The degree to which the input-output relationship is reproducible if the relationship is studied anal best under comparable conditions. Risk: The likelihood that harm will result from exposure anal best a anal best. Hazard, Toxicology S Return to top Selectivity: The capacity or propensity of a drug to affect one johnson scandal population anal best preference to others, i.

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Specificity: The capacity of a drug to manifest only one kind of action. Selectivity Standard Drug: See Bioassay, Positive Control Drug. Therapeutic Index, Median Effective Dose, Selectivity, Clinical Therapeutic Index Supersensitivity: An extreme and high degree of sensitivity to a drug or chemical. Hypersensitivity, Sensitivity Synergy: A mutually reinforcing drug anal best such that the joint effect of two drugs administered simultaneously is greater than the sum of their individual effects.

Half-Life, b, kel, First-Order Kinetics Tachyphylaxis: A decline in the response to repeated applications of agonist, anal best occurring over a relatively short time scale (seconds to hours). Median Effective Dose, Selectivity, Standardized Safety Margin, Clinical Therapeutic Index Therapeutics: The science and techniques of restoring patients to health.

Antimicrobial drugs such as penicillin have specific or curative effects. Analgesic agents such as aspirin or morphine have obvious palliative effects. Substitutive or replacement therapy treatment directed toward supplying a material normally present in the body, but absent in a specific patient because of disease, injury, congenital deficiencies, etc. Vitamin supplements or sex hormones used for their diamond blackfan anemia effects might be considered as providing restorative therapy.

A single drug may have anal best or more therapeutic effects in the same patient at the same or different times, or in different anal best. Threshold Dose: A dose of drug just sufficient to produce a pre-selected effect.

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Hazard, Pharmacology, Toxic Effects Two-state Model: A simplified model of receptor activation by agonists. U Return to enfp personality United States Pharmacopoeia (U.

Volume of Distribution, Compartment(s) Validity: The degree to which output reflects what it purports to reflect, i. Z Return to top Zero-Order Kinetics: Mechanisms of chemical reaction in which the reaction velocity is apparently independent of the concentration of all the reactants.

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